Regulatory Status
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Safety Data
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Expert Verdict
LC50 of 217 µg/ml in brine shrimp lethality assay indicates cytotoxic classification; contains vasicine (pyrroloquinazoline alkaloid) with known abortifacient and uterotonic activity contraindicated in pregnancy-targeted products; no dermal safety studies identified; alkaloid content must be quantified and controlled.
Regulatory Flags
Frequently Asked Questions
Is Justicia Adhatoda Leaf Extract safe in cosmetics?
LC50 of 217 µg/ml in brine shrimp lethality assay indicates cytotoxic classification; contains vasicine (pyrroloquinazoline alkaloid) with known abortifacient and uterotonic activity contraindicated in pregnancy-targeted products; no dermal safety studies identified; alkaloid content must be quantified and controlled. The EU classifies Justicia Adhatoda Leaf Extract as "prohibited". Safety rating: MODERATE.
Is Justicia Adhatoda Leaf Extract allowed in the EU?
Justicia Adhatoda Leaf Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Justicia Adhatoda Leaf Extract do in cosmetics?
Justicia Adhatoda Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng (no unique CAS established).
What is the Margin of Safety for Justicia Adhatoda Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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