Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate

INCI: KLUYVEROMYCES/LACTOBACILLUS/PAEONIA LACTIFLORA ROOT OIL FERMENT FILTRATE

CAS Number
Not assigned
Function
Antioxidant, skin conditioning, skin soothing/protecting (based on the well-documented pharmacology of Paeonia lactiflora and analogous entries in the series)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; no specific prohibitions or restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR assessment. Paeoniflorin (the major active glucoside in P. lactiflora) is pharmacologically potent - concentration limits should be self-imposed based on safety dossier. Sensitization risk considered low but data is limited for the fermented oil form. Paeonia lactiflora (Chinese/white peony) root contains paeoniflorin with well-documented anti-inflammatory, antioxidant, and immunomodulatory activity. Fermentation may break down high-MW glycosides into more skin-permeable aglycones

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Concern Level: Moderate

Regulatory Flags

plant-oil potential-allergen

Frequently Asked Questions

Is Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate safe in cosmetics?

No CIR assessment. Paeoniflorin (the major active glucoside in P. lactiflora) is pharmacologically potent - concentration limits should be self-imposed based on safety dossier. Sensitization risk considered low but data is limited for the fermented oil form. Paeonia lactiflora (Chinese/white peony) root contains paeoniflorin with well-documented anti-inflammatory, antioxidant, and immunomodulatory activity. Fermentation may break down high-MW glycosides into more skin-permeable aglycones The EU classifies Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate as "permitted". Safety rating: MODERATE.

Is Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate allowed in the EU?

Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate do in cosmetics?

Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate functions as: Antioxidant, skin conditioning, skin soothing/protecting (based on the well-documented pharmacology of Paeonia lactiflora and analogous entries in the series). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Kluyveromyces/Lactobacillus/Paeonia Lactiflora Root Oil Ferment Filtrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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