Kushenols / Kurarinone
INCI: NO STANDARD SINGLE INCI NAME - THESE ARE PHYTOCHEMICAL COMPOUNDS, NOT REGISTERED COSMETIC INGREDIENTS PER SE. THE SOURCE PLANT EXTRACT IS TYPICALLY LISTED AS SOPHORA FLAVESCENS ROOT EXTRACT IN INCI NOMENCLATURE
Regulatory Status
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Safety Data
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Expert Verdict
Prenylated flavonoids can have potent biological activity. Kurarinone has documented estrogenic and cytotoxic properties in pharmacological studies, warranting caution at high concentrations. Standardization of extract to specific kushenol/kurarinone levels is advisable. Kushenols and kurarinone are lavandulylated flavanones isolated from Sophora flavescens (ku shen in TCM). They exhibit diverse bioactivities including anti-allergic, anti-inflammatory, and melanogenesis-inhibitory effects. In...
Frequently Asked Questions
Is Kushenols / Kurarinone safe in cosmetics?
Prenylated flavonoids can have potent biological activity. Kurarinone has documented estrogenic and cytotoxic properties in pharmacological studies, warranting caution at high concentrations. Standardization of extract to specific kushenol/kurarinone levels is advisable. Kushenols and kurarinone are lavandulylated flavanones isolated from Sophora flavescens (ku shen in TCM). They exhibit diverse bioactivities including anti-allergic, anti-inflammatory, and melanogenesis-inhibitory effects. In... The EU classifies Kushenols / Kurarinone as "permitted". Safety rating: MODERATE.
Is Kushenols / Kurarinone allowed in the EU?
Kushenols / Kurarinone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Kushenols / Kurarinone do in cosmetics?
Kushenols / Kurarinone functions as: Anti-inflammatory, antioxidant, anti-allergic, tyrosinase inhibition (melanin suppression). It is classified as a cosmetic ingredient in our database. CAS number: Kurarinone: 1049662-21-6; Kushenol K: 101236-49-1; Kushenol N: 102490-65-3; multiple other kushenols exist with distinct CAS numbers.
What is the Margin of Safety for Kushenols / Kurarinone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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