Is Lactobacillus Ferment Lysate safe in cosmetics?
Lactobacillus Ferment Lysate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Lactobacillus Ferment Lysate
INCI: LACTOBACILLUS FERMENT LYSATE
Lactobacillus Ferment Lysate (CAS Not specifically assigned (biological fermentation product)) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not specifically assigned (biological fermentation product)
View industrial chemical safety profile →
Function
Skin Conditioning, Skin Protecting
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR assessed — found safe as used in cosmetics (assessment published 2025)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Lactobacillus Ferment Lysate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "85", "estimated_cost_per_kg_usd_high": "160", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Europe/US", "bulk_discount_threshold_kg": "25", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Yogurt E…
fermentation
{"cas_number": "proprietary", "ingredient_class": "ferment_lysate", "production_organism": "Lactobacillus", "fermentation_type": "anaerobic", "substrate_feedstock": "plant material, MRS broth", "bioactive_compounds_produced": "lactic acid, bacteriocins, exopolysaccharides, peptides", "mechanism_of_action_skin": "microbiome support, pH regulation, antimicrobial peptide production", "skin_benefit_pr…
microbiome_impact
{"microbiome_effect": "positive", "prebiotic": "yes", "probiotic_compatible": "yes", "antimicrobial_spectrum": "selective", "preservative_effect_on_microbiome": "Postbiotic; cell wall fragments; supports microbiome balance; anti-inflammatory", "gut_microbiome_risk": "low", "microbiome_recovery_time": "<3 days", "selective_antimicrobial": "yes", "beneficial_bacteria_support": "S. epidermidis, Lacto…
preservative
{"preservative_class": "Fermented extract", "antimicrobial_spectrum_bacteria_gp": "Moderate", "antimicrobial_spectrum_bacteria_gn": "Good", "antimicrobial_spectrum_yeast": "Yes", "antimicrobial_spectrum_mold": "Moderate", "mic_staph_aureus_ppm": "1100", "mic_e_coli_ppm": "1300", "mic_pseudomonas_ppm": "1550", "mic_candida_albicans_ppm": "2100", "mic_aspergillus_niger_ppm": "3100", "challenge_test_…
Expert Verdict
Expert safety assessment and concern-level summary for Lactobacillus Ferment Lysate.
Frequently Asked Questions
Is Lactobacillus Ferment Lysate allowed in the EU?
Lactobacillus Ferment Lysate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lactobacillus Ferment Lysate do in cosmetics?
Lactobacillus Ferment Lysate functions as: Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (biological fermentation product).
Compliance Tools
Check Lactobacillus Ferment Lysate compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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