Larrea Divaricata Leaf Extract
Regulatory Status
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Safety Data
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Expert Verdict
NDGA-related hepatotoxicity concerns present; leaf extract may concentrate resinous NDGA-containing fractions without differentiated safety data from whole-plant extract; NDGA quantification and toxicological justification required for any CPSR submission.
Regulatory Flags
Frequently Asked Questions
Is Larrea Divaricata Leaf Extract safe in cosmetics?
NDGA-related hepatotoxicity concerns present; leaf extract may concentrate resinous NDGA-containing fractions without differentiated safety data from whole-plant extract; NDGA quantification and toxicological justification required for any CPSR submission. The EU classifies Larrea Divaricata Leaf Extract as "permitted". Safety rating: POOR.
Is Larrea Divaricata Leaf Extract allowed in the EU?
Larrea Divaricata Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What is the Margin of Safety for Larrea Divaricata Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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