Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Lauramide MEA. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Generally well-tolerated. Lower nitrosamine risk compared to DEA-based amides since monoethanolamine (MEA) is a primary amine (not directly nitrosatable). However, secondary amine impurities in MEA feedstock must be controlled. Mild skin irritation possible at high concentrations. White waxy solid at room temperature (m.p. 88-89°C). Produced by reacting coconut-derived lauric acid with monoethanolamine. Molecular formula C₁₄H₂₉NO₂, MW 243.39. Provides rich, creamy lather and thickening withou...
Frequently Asked Questions
Is Lauramide MEA safe in cosmetics?
Generally well-tolerated. Lower nitrosamine risk compared to DEA-based amides since monoethanolamine (MEA) is a primary amine (not directly nitrosatable). However, secondary amine impurities in MEA feedstock must be controlled. Mild skin irritation possible at high concentrations. White waxy solid at room temperature (m.p. 88-89°C). Produced by reacting coconut-derived lauric acid with monoethanolamine. Molecular formula C₁₄H₂₉NO₂, MW 243.39. Provides rich, creamy lather and thickening withou... The EU classifies Lauramide MEA as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Lauramide MEA allowed in the EU?
Lauramide MEA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lauramide MEA do in cosmetics?
Lauramide MEA functions as: Antistatic, cleansing, emulsifying, foam boosting, skin conditioning, smoothing, surfactant, and viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 142-78-9.
What is the Margin of Safety for Lauramide MEA?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Lauramide MEA?
The NOAEL (No Observed Adverse Effect Level) for Lauramide MEA is >=1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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