Good Cosmetic Ingredient NOAEL Data

Lauramidopropyl Hydroxysultaine

CAS Number
13197-76-7
Function
Anti-static agent; Cleaning agent; Foamant; Softener and conditioner; Surfactant (surface active agent); Viscosity modifier
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR: safe when DMAPA impurity minimized

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Lauramidopropyl Hydroxysultaine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 0.5 other oral rat oral REACH

Expert Verdict

DMAPA impurity must remain <3 ppm; CIR Panel urges manufacturers to minimize DMAPA content; ocular irritation predicted in vitro at higher concentrations (โ‰ฅ1.25%); generally mild and well-tolerated

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Concern Level: Low

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Lauramidopropyl Hydroxysultaine safe in cosmetics?

DMAPA impurity must remain <3 ppm; CIR Panel urges manufacturers to minimize DMAPA content; ocular irritation predicted in vitro at higher concentrations (โ‰ฅ1.25%); generally mild and well-tolerated The EU classifies Lauramidopropyl Hydroxysultaine as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Lauramidopropyl Hydroxysultaine allowed in the EU?

Lauramidopropyl Hydroxysultaine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lauramidopropyl Hydroxysultaine do in cosmetics?

Lauramidopropyl Hydroxysultaine functions as: Anti-static agent; Cleaning agent; Foamant; Softener and conditioner; Surfactant (surface active agent); Viscosity modifier. It is classified as a cosmetic ingredient in our database. CAS number: 13197-76-7.

What is the Margin of Safety for Lauramidopropyl Hydroxysultaine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Lauramidopropyl Hydroxysultaine?

The NOAEL (No Observed Adverse Effect Level) for Lauramidopropyl Hydroxysultaine is 0.5 other based on a oral study via oral route in rat. Source: REACH.

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