Laureth-3 Phosphate

INCI: LAURETH-3 PHOSPHATE

CAS Number
39322-78-6 (phosphoric acid ester of laureth-3; note: Laureth-3 itself is CAS 68439-50-9)
Function
Cleansing, surfactant (cleansing)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed under general cosmetic regulations; subject to 1,4-dioxane scrutiny - New York State mandates โ‰ค2 ppm by December 2026, California Prop 65 lists 1,4-dioxane as a carcinogen

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

1,4-Dioxane contamination is the primary concern - a byproduct of ethoxylation; must be stripped/purified during manufacturing; ethylene oxide residues should also be monitored; mild skin irritation potential at high concentrations. Anionic phosphate ester surfactant (differs from the cationic quaternary ammonium compounds in \#1-9); provides excellent cleansing with good foam characteristics; phosphate esters are generally more hydrotropic and less irritating than sulfate equivalents; compat...

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Concern Level: Moderate

Frequently Asked Questions

Is Laureth-3 Phosphate safe in cosmetics?

1,4-Dioxane contamination is the primary concern - a byproduct of ethoxylation; must be stripped/purified during manufacturing; ethylene oxide residues should also be monitored; mild skin irritation potential at high concentrations. Anionic phosphate ester surfactant (differs from the cationic quaternary ammonium compounds in \#1-9); provides excellent cleansing with good foam characteristics; phosphate esters are generally more hydrotropic and less irritating than sulfate equivalents; compat... The EU classifies Laureth-3 Phosphate as "permitted". Safety rating: MODERATE.

Is Laureth-3 Phosphate allowed in the EU?

Laureth-3 Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Laureth-3 Phosphate do in cosmetics?

Laureth-3 Phosphate functions as: Cleansing, surfactant (cleansing). It is classified as a cosmetic ingredient in our database. CAS number: 39322-78-6 (phosphoric acid ester of laureth-3; note: Laureth-3 itself is CAS 68439-50-9).

What is the Margin of Safety for Laureth-3 Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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