Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Lauryl Betaine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 350 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 250 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Concentration-dependent irritation: no irritation at 0.1%, but observed at ≥1% in human studies. Ocular irritant at ≥10%. Must formulate to be non-irritating. Cross-reactivity with cocamidopropyl betaine (CAPB) in sensitized individuals is a theoretical concern.
Regulatory Flags
Frequently Asked Questions
Is Lauryl Betaine safe in cosmetics?
Concentration-dependent irritation: no irritation at 0.1%, but observed at ≥1% in human studies. Ocular irritant at ≥10%. Must formulate to be non-irritating. Cross-reactivity with cocamidopropyl betaine (CAPB) in sensitized individuals is a theoretical concern. The EU classifies Lauryl Betaine as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is Lauryl Betaine allowed in the EU?
Lauryl Betaine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lauryl Betaine do in cosmetics?
Lauryl Betaine functions as: Surfactant, cleansing, emulsifying, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 683-10-3.
What is the Margin of Safety for Lauryl Betaine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Lauryl Betaine?
The NOAEL (No Observed Adverse Effect Level) for Lauryl Betaine is 350 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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