Moderate Cosmetic Ingredient NOAEL Data

Laurylpyridinium Chloride

INCI: LAURYLPYRIDINIUM CHLORIDE

CAS Number
104-74-5
Function
Antimicrobial, antistatic, deodorant, surfactant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes SCCS Opinion

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Laurylpyridinium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 200 other oral mouse oral REACH
NOAEL 40 mg/kg bw/day oral rat oral REACH
NOAEL 200 other other code:3544 oral REACH

Expert Verdict

Laurylpyridinium chloride is an antimicrobial surfactant with moderate safety profile and established low sensitization risk.

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Concern Level: Moderate

Frequently Asked Questions

Is Laurylpyridinium Chloride safe in cosmetics?

Laurylpyridinium chloride is an antimicrobial surfactant with moderate safety profile and established low sensitization risk. The EU classifies Laurylpyridinium Chloride as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is Laurylpyridinium Chloride allowed in the EU?

Laurylpyridinium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Laurylpyridinium Chloride do in cosmetics?

Laurylpyridinium Chloride functions as: Antimicrobial, antistatic, deodorant, surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 104-74-5.

What is the Margin of Safety for Laurylpyridinium Chloride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Laurylpyridinium Chloride?

The NOAEL (No Observed Adverse Effect Level) for Laurylpyridinium Chloride is 200 other based on a oral study via oral route in mouse. A total of 3 study endpoints are available. Source: REACH.

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