Leontopodium Alpinum Callus Culture Extract

INCI: LEONTOPODIUM ALPINUM CALLUS CULTURE EXTRACT

CAS Number
Not specifically assigned (parent plant extract CAS: 391900-47-3)
Function
Antioxidant, Hair Conditioning, Humectant, Skin Protecting
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally well-tolerated; plant stem cell extracts undergo extensive in vitro processing, reducing allergenic plant protein content; no significant adverse event reports. Marketed under the trade name Majestem; derived from dedifferentiated Edelweiss plant stem cells cultivated in bioreactors; contains leontopodic acids A and B; in-vivo studies showed neck skin tightening of −10.6% to −56% in three weeks and crow's feet reduction (surface −11% to −75%) after six weeks; recommended use level 1...

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen natural-origin

Frequently Asked Questions

Is Leontopodium Alpinum Callus Culture Extract safe in cosmetics?

Generally well-tolerated; plant stem cell extracts undergo extensive in vitro processing, reducing allergenic plant protein content; no significant adverse event reports. Marketed under the trade name Majestem; derived from dedifferentiated Edelweiss plant stem cells cultivated in bioreactors; contains leontopodic acids A and B; in-vivo studies showed neck skin tightening of −10.6% to −56% in three weeks and crow's feet reduction (surface −11% to −75%) after six weeks; recommended use level 1... The EU classifies Leontopodium Alpinum Callus Culture Extract as "permitted". Safety rating: MODERATE.

Is Leontopodium Alpinum Callus Culture Extract allowed in the EU?

Leontopodium Alpinum Callus Culture Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Leontopodium Alpinum Callus Culture Extract do in cosmetics?

Leontopodium Alpinum Callus Culture Extract functions as: Antioxidant, Hair Conditioning, Humectant, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (parent plant extract CAS: 391900-47-3).

What is the Margin of Safety for Leontopodium Alpinum Callus Culture Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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