Leonurus Cardiaca Extract (Motherwort)

INCI: LEONURUS CARDIACA EXTRACT

CAS Number
84012-28-2 (Leonurus Cardiaca Extract)
Function
Skin Conditioning, Tonic, Soothing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction; no CIR report on record

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains leonurine and stachydrine with pharmacological oral uterotonic and cardiac activity at high doses, but topical cosmetic concentrations remain far below systemic effect thresholds; formulators should document that dermal exposure does not approach systemic levels; limited formal cosmetic safety assessment data requiring independent safety substantiation for CPSR and MoCRA compliance.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Leonurus Cardiaca Extract (Motherwort) safe in cosmetics?

Contains leonurine and stachydrine with pharmacological oral uterotonic and cardiac activity at high doses, but topical cosmetic concentrations remain far below systemic effect thresholds; formulators should document that dermal exposure does not approach systemic levels; limited formal cosmetic safety assessment data requiring independent safety substantiation for CPSR and MoCRA compliance. The EU classifies Leonurus Cardiaca Extract (Motherwort) as "permitted". Safety rating: GOOD.

Is Leonurus Cardiaca Extract (Motherwort) allowed in the EU?

Leonurus Cardiaca Extract (Motherwort) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Leonurus Cardiaca Extract (Motherwort) do in cosmetics?

Leonurus Cardiaca Extract (Motherwort) functions as: Skin Conditioning, Tonic, Soothing. It is classified as a cosmetic ingredient in our database. CAS number: 84012-28-2 (Leonurus Cardiaca Extract).

What is the Margin of Safety for Leonurus Cardiaca Extract (Motherwort)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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