(Licorice/Reynoutria Japonica) Root/Stem Extract

INCI: (LICORICE/REYNOUTRIA JAPONICA) ROOT/STEM EXTRACT

CAS Number
None assigned for the blend (individual: Reynoutria japonica extract = 90604-49-2)
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; licorice root extracts have CIR review but not this specific blend

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Reynoutria japonica (Japanese knotweed) is a primary natural source of trans-resveratrol and emodin; emodin is an anthraquinone with phototoxicity and genotoxicity concerns flagged by EFSA; glycyrrhizin raises similar safety concerns.

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is (Licorice/Reynoutria Japonica) Root/Stem Extract safe in cosmetics?

Reynoutria japonica (Japanese knotweed) is a primary natural source of trans-resveratrol and emodin; emodin is an anthraquinone with phototoxicity and genotoxicity concerns flagged by EFSA; glycyrrhizin raises similar safety concerns. The EU classifies (Licorice/Reynoutria Japonica) Root/Stem Extract as "permitted". Safety rating: MODERATE.

Is (Licorice/Reynoutria Japonica) Root/Stem Extract allowed in the EU?

(Licorice/Reynoutria Japonica) Root/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does (Licorice/Reynoutria Japonica) Root/Stem Extract do in cosmetics?

(Licorice/Reynoutria Japonica) Root/Stem Extract functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: None assigned for the blend (individual: Reynoutria japonica extract = 90604-49-2).

What is the Margin of Safety for (Licorice/Reynoutria Japonica) Root/Stem Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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