Lysophosphatidic Acid

INCI: LYSOPHOSPHATIDIC ACID

CAS Number
Not assigned a unique CAS in CIR report (component of lecithin mixtures)
Function
Hair conditioning, humectant, skin protectant, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel: "safe in the present practices of use and concentration" as part of the 17-phosphoglyceride group review (2020)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

LPA is a bioactive signaling lipid at physiological concentrations; however, CIR concluded dermal application at cosmetic use levels does not produce physiologic effects. Very low reported use (2 formulations in VCRP data).

โš ๏ธ
Concern Level: Low

Frequently Asked Questions

Is Lysophosphatidic Acid safe in cosmetics?

LPA is a bioactive signaling lipid at physiological concentrations; however, CIR concluded dermal application at cosmetic use levels does not produce physiologic effects. Very low reported use (2 formulations in VCRP data). The EU classifies Lysophosphatidic Acid as "permitted". Safety rating: GOOD.

Is Lysophosphatidic Acid allowed in the EU?

Lysophosphatidic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lysophosphatidic Acid do in cosmetics?

Lysophosphatidic Acid functions as: Hair conditioning, humectant, skin protectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned a unique CAS in CIR report (component of lecithin mixtures).

What is the Margin of Safety for Lysophosphatidic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Lysophosphatidic Acid in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Lysophosphatidic Acid in your formulation.