Lysophosphatidylcholinylchlorin e6
INCI: LYSOPHOSPHATIDYLCHOLINYLCHLORIN E6
Regulatory Status
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Safety Data
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Expert Verdict
Major flag. Chlorin e6 is a porphyrin photosensitizer; UV/visible light exposure could cause phototoxic reactions. This ingredient has no CIR or SCCS review. Do NOT include in a cosmetic formulation without a full phototoxicity study (OECD TG 432), in vitro 3T3 NRU phototoxicity assay, and a justified MoS calculation. Not appropriate for leave-on products without robust safety data.
Regulatory Flags
Frequently Asked Questions
Is Lysophosphatidylcholinylchlorin e6 safe in cosmetics?
Major flag. Chlorin e6 is a porphyrin photosensitizer; UV/visible light exposure could cause phototoxic reactions. This ingredient has no CIR or SCCS review. Do NOT include in a cosmetic formulation without a full phototoxicity study (OECD TG 432), in vitro 3T3 NRU phototoxicity assay, and a justified MoS calculation. Not appropriate for leave-on products without robust safety data. The EU classifies Lysophosphatidylcholinylchlorin e6 as "permitted". Safety rating: POOR.
Is Lysophosphatidylcholinylchlorin e6 allowed in the EU?
Lysophosphatidylcholinylchlorin e6 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lysophosphatidylcholinylchlorin e6 do in cosmetics?
Lysophosphatidylcholinylchlorin e6 functions as: Skin conditioning (listed function); structurally a chlorin e6–phospholipid conjugate used primarily in photodynamic research. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published — specialty photosensitizer conjugate.
What is the Margin of Safety for Lysophosphatidylcholinylchlorin e6?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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