Maclura Cochinchinensis Leaf Prenylflavonoids

INCI: MACLURA COCHINCHINENSIS LEAF PRENYLFLAVONOIDS

CAS Number
2243209-55-2
Function
Skin conditioning agent. Antioxidant activity via flavonoid mechanisms (protects against light-induced skin aging, stimulates cellular repair)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not listed on the FDA's prohibited or restricted ingredients list; regulated as a cosmetic ingredient under general FDCA provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited standalone safety data; function not fully specified in CosIng. As a prenylflavonoid class, generally regarded as low-risk, but no formal CIR or SCCS opinion exists. Isolated from leaves of Maclura cochinchinensis (Moraceae); prenylflavonoids protect plant cell nuclei from UV and are leveraged in cosmetics for their antioxidative protection potential

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Concern Level: Moderate

Frequently Asked Questions

Is Maclura Cochinchinensis Leaf Prenylflavonoids safe in cosmetics?

Limited standalone safety data; function not fully specified in CosIng. As a prenylflavonoid class, generally regarded as low-risk, but no formal CIR or SCCS opinion exists. Isolated from leaves of Maclura cochinchinensis (Moraceae); prenylflavonoids protect plant cell nuclei from UV and are leveraged in cosmetics for their antioxidative protection potential The EU classifies Maclura Cochinchinensis Leaf Prenylflavonoids as "permitted". Safety rating: MODERATE.

Is Maclura Cochinchinensis Leaf Prenylflavonoids allowed in the EU?

Maclura Cochinchinensis Leaf Prenylflavonoids EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Maclura Cochinchinensis Leaf Prenylflavonoids do in cosmetics?

Maclura Cochinchinensis Leaf Prenylflavonoids functions as: Skin conditioning agent. Antioxidant activity via flavonoid mechanisms (protects against light-induced skin aging, stimulates cellular repair). It is classified as a cosmetic ingredient in our database. CAS number: 2243209-55-2.

What is the Margin of Safety for Maclura Cochinchinensis Leaf Prenylflavonoids?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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