Manganese PCA

INCI: MANGANESE PCA

CAS Number
Not assigned in CosIng or SpecialChem databases (COSING REF No: 35159)
Function
Humectant, moisturising agent, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed as a cosmetic ingredient; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally considered safe. The manganese salt of pyrrolidone carboxylic acid (PCA) is a naturally derived amino acid compound with no significant reported adverse effects at recommended concentrations. Recommended dosage of 0.5-1.5% in formulations. Acts as an antioxidant by binding to superoxide dismutase (SOD) enzymes that neutralize free radicals. Enhances cellular longevity and helps prevent visible signs of skin aging

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Manganese PCA safe in cosmetics?

Generally considered safe. The manganese salt of pyrrolidone carboxylic acid (PCA) is a naturally derived amino acid compound with no significant reported adverse effects at recommended concentrations. Recommended dosage of 0.5-1.5% in formulations. Acts as an antioxidant by binding to superoxide dismutase (SOD) enzymes that neutralize free radicals. Enhances cellular longevity and helps prevent visible signs of skin aging The EU classifies Manganese PCA as "permitted". Safety rating: MODERATE.

Is Manganese PCA allowed in the EU?

Manganese PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Manganese PCA do in cosmetics?

Manganese PCA functions as: Humectant, moisturising agent, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng or SpecialChem databases (COSING REF No: 35159).

What is the Margin of Safety for Manganese PCA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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