Moderate Cosmetic Ingredient

MEA-Hydrolyzed Silk

INCI: MEA-HYDROLYZED SILK

CAS Number
Not individually assigned (derived from hydrolyzed silk protein complexed with monoethanolamine)
Function
Hair conditioning (imparts combability, suppleness, softness, shine, volume); skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Allowed; CIR Expert Panel found ethanolamine salts safe in rinse-off products when formulated to be non-irritating and when not used in products where N-nitroso compounds may form

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Nitrosamine contamination risk; potential DEA impurity in the ethanolamine moiety. Animal/synthetic origin (silkworm-derived protein); provides amino acids that bind to damaged hair; film-forming on skin and hair

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Concern Level: Moderate

Frequently Asked Questions

Is MEA-Hydrolyzed Silk safe in cosmetics?

Nitrosamine contamination risk; potential DEA impurity in the ethanolamine moiety. Animal/synthetic origin (silkworm-derived protein); provides amino acids that bind to damaged hair; film-forming on skin and hair The EU classifies MEA-Hydrolyzed Silk as "restricted". Safety rating: MODERATE.

Is MEA-Hydrolyzed Silk allowed in the EU?

MEA-Hydrolyzed Silk EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does MEA-Hydrolyzed Silk do in cosmetics?

MEA-Hydrolyzed Silk functions as: Hair conditioning (imparts combability, suppleness, softness, shine, volume); skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (derived from hydrolyzed silk protein complexed with monoethanolamine).

What is the Margin of Safety for MEA-Hydrolyzed Silk?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check MEA-Hydrolyzed Silk compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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