Melia Azadirachta Bark Extract

INCI: MELIA AZADIRACHTA BARK EXTRACT

CAS Number
10
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Data Sufficiency

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited cosmetic-specific toxicological data and CAS assignment ambiguity create regulatory risk. Bark contains different phytochemical profile than seeds with lower azadirachtin and higher tannins, but this differentiation is not yet recognized in CLP classification. Regulatory counsel recommended before EU market placement.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Melia Azadirachta Bark Extract safe in cosmetics?

Limited cosmetic-specific toxicological data and CAS assignment ambiguity create regulatory risk. Bark contains different phytochemical profile than seeds with lower azadirachtin and higher tannins, but this differentiation is not yet recognized in CLP classification. Regulatory counsel recommended before EU market placement. The EU classifies Melia Azadirachta Bark Extract as "permitted". Safety rating: MODERATE.

Is Melia Azadirachta Bark Extract allowed in the EU?

Melia Azadirachta Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Melia Azadirachta Bark Extract do in cosmetics?

Melia Azadirachta Bark Extract functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 10.

What is the Margin of Safety for Melia Azadirachta Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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