Mercaptotriazole Caffeamide

INCI: MERCAPTOTRIAZOLE CAFFEAMIDE (LISTED IN COSING)

CAS Number
Not widely cataloged in major databases - this is a specialty/novel ingredient.
Function
Antioxidant / skin conditioning - combines the radical-scavenging properties of a caffeic acid amide moiety with a mercaptotriazole heterocyclic nucleus.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; no specific prohibition. As a novel ingredient, it would fall under the manufacturer's responsibility for safety substantiation.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published toxicological data; the mercapto-triazole core requires evaluation for sensitization potential; caffeic acid derivatives have generally favorable safety profiles but may exhibit phototoxicity at high concentrations.. Hybrid molecule designed to deliver dual antioxidant mechanisms - thiol-mediated radical scavenging from the mercaptotriazole ring and polyphenol-type protection from the caffeamide portion.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Mercaptotriazole Caffeamide safe in cosmetics?

Limited published toxicological data; the mercapto-triazole core requires evaluation for sensitization potential; caffeic acid derivatives have generally favorable safety profiles but may exhibit phototoxicity at high concentrations.. Hybrid molecule designed to deliver dual antioxidant mechanisms - thiol-mediated radical scavenging from the mercaptotriazole ring and polyphenol-type protection from the caffeamide portion. The EU classifies Mercaptotriazole Caffeamide as "permitted". Safety rating: MODERATE.

Is Mercaptotriazole Caffeamide allowed in the EU?

Mercaptotriazole Caffeamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mercaptotriazole Caffeamide do in cosmetics?

Mercaptotriazole Caffeamide functions as: Antioxidant / skin conditioning - combines the radical-scavenging properties of a caffeic acid amide moiety with a mercaptotriazole heterocyclic nucleus.. It is classified as a cosmetic ingredient in our database. CAS number: Not widely cataloged in major databases - this is a specialty/novel ingredient..

What is the Margin of Safety for Mercaptotriazole Caffeamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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