Metal Complexes Peptides

INCI: COPPER TRIPEPTIDE-1

CAS Number
Category term — no single CAS; e.g., Copper Tripeptide-1 (GHK-Cu) = 89030-95-5
Function
Skin conditioning, anti-aging (collagen stimulation, wound healing support)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR reviewed Tripeptide-1, Hexapeptide-12, their metal salts and fatty acyl derivatives — concluded safe as used in current practices and concentrations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Metal ion component (Cu, Mn, Zn) must be controlled for concentration; free copper ions at high levels can be pro-oxidant; ensure use within CIR-reviewed concentrations

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Concern Level: Low

Frequently Asked Questions

Is Metal Complexes Peptides safe in cosmetics?

Metal ion component (Cu, Mn, Zn) must be controlled for concentration; free copper ions at high levels can be pro-oxidant; ensure use within CIR-reviewed concentrations The EU classifies Metal Complexes Peptides as "permitted". Safety rating: GOOD.

Is Metal Complexes Peptides allowed in the EU?

Metal Complexes Peptides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Metal Complexes Peptides do in cosmetics?

Metal Complexes Peptides functions as: Skin conditioning, anti-aging (collagen stimulation, wound healing support). It is classified as a cosmetic ingredient in our database. CAS number: Category term — no single CAS; e.g., Copper Tripeptide-1 (GHK-Cu) = 89030-95-5.

What is the Margin of Safety for Metal Complexes Peptides?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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