Methacryloyloxypropyl Polysilsesquioxane

INCI: METHACRYLOYLOXYPROPYL POLYSILSESQUIOXANE (LISTED IN COSING)

CAS Number
Not assigned a single CAS (polymeric/oligomeric silsesquioxane with methacrylate functionality; cage or ladder structure varies)
Function
Film forming, hair conditioning, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically restricted; silsesquioxanes are generally regarded as safe in cosmetic applications

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low systemic toxicity; inorganic-organic hybrid material with high thermal stability; potential for occlusion at high concentrations. Polysilsesquioxane (PSSQ) has a cage-like (T8) or ladder siloxane backbone with the empirical formula (RSiOโ‚.โ‚…)โ‚™, providing hardness, thermal stability, and optical clarity superior to linear silicones. The methacrylate group enables UV or radical curing into durable, breathable films with excellent light-scattering properties for soft-focus effects.

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Concern Level: High

Frequently Asked Questions

Is Methacryloyloxypropyl Polysilsesquioxane safe in cosmetics?

Low systemic toxicity; inorganic-organic hybrid material with high thermal stability; potential for occlusion at high concentrations. Polysilsesquioxane (PSSQ) has a cage-like (T8) or ladder siloxane backbone with the empirical formula (RSiOโ‚.โ‚…)โ‚™, providing hardness, thermal stability, and optical clarity superior to linear silicones. The methacrylate group enables UV or radical curing into durable, breathable films with excellent light-scattering properties for soft-focus effects. The EU classifies Methacryloyloxypropyl Polysilsesquioxane as "prohibited". Safety rating: MODERATE.

Is Methacryloyloxypropyl Polysilsesquioxane allowed in the EU?

Methacryloyloxypropyl Polysilsesquioxane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Methacryloyloxypropyl Polysilsesquioxane do in cosmetics?

Methacryloyloxypropyl Polysilsesquioxane functions as: Film forming, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned a single CAS (polymeric/oligomeric silsesquioxane with methacrylate functionality; cage or ladder structure varies).

What is the Margin of Safety for Methacryloyloxypropyl Polysilsesquioxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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