Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Growth factor with theoretical proliferative risk at supra-physiological doses; potential E. coli host-cell protein and endotoxin residuals if inadequately purified; no CIR or SCCS evaluation available.
Frequently Asked Questions
Is Methionyl sh-Polypeptide-1 safe in cosmetics?
Growth factor with theoretical proliferative risk at supra-physiological doses; potential E. coli host-cell protein and endotoxin residuals if inadequately purified; no CIR or SCCS evaluation available. The EU classifies Methionyl sh-Polypeptide-1 as "permitted". Safety rating: MODERATE.
Is Methionyl sh-Polypeptide-1 allowed in the EU?
Methionyl sh-Polypeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methionyl sh-Polypeptide-1 do in cosmetics?
Methionyl sh-Polypeptide-1 functions as: Skin conditioning — recombinant basic Fibroblast Growth Factor (bFGF); stimulates fibroblast proliferation, collagen/elastin synthesis. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (recombinant bFGF variant; reference CAS 106096-93-9 for rh-bFGF).
What is the Margin of Safety for Methionyl sh-Polypeptide-1?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Methionyl sh-Polypeptide-1 compliance across multiple jurisdictions:
Related Ingredients
Is Methionyl sh-Polypeptide-1 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methionyl sh-Polypeptide-1 in your formulation.