Moderate Cosmetic Ingredient

Methoxy Amodimethicone/Silsesquioxane Copolymer

INCI: METHOXY AMODIMETHICONE/SILSESQUIOXANE COPOLYMER

CAS Number
Not assigned (polymer). COSING Ref No: 57950, PCPC No: 16775.
Function
Film forming, hair conditioning, skin conditioning.
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 1.92%
🇺🇸 US Status permitted
US Notes Allowed; not specifically prohibited or restricted.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally well-tolerated silicone hybrid. CIR has reviewed polysilsesquioxane-class ingredients. Standard silicone safety profile - low irritation potential, non-comedogenic at typical use levels.. Copolymer of methyl trimethoxysilane and methoxy amodimethicone monomers; provides a smooth film, soft focus effect, and conditioning properties in color cosmetics.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Methoxy Amodimethicone/Silsesquioxane Copolymer safe in cosmetics?

Generally well-tolerated silicone hybrid. CIR has reviewed polysilsesquioxane-class ingredients. Standard silicone safety profile - low irritation potential, non-comedogenic at typical use levels.. Copolymer of methyl trimethoxysilane and methoxy amodimethicone monomers; provides a smooth film, soft focus effect, and conditioning properties in color cosmetics. The EU classifies Methoxy Amodimethicone/Silsesquioxane Copolymer as "permitted". Safety rating: MODERATE.

Is Methoxy Amodimethicone/Silsesquioxane Copolymer allowed in the EU?

Methoxy Amodimethicone/Silsesquioxane Copolymer EU regulatory status: permitted. Maximum allowed concentration: 1.92%. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy Amodimethicone/Silsesquioxane Copolymer do in cosmetics?

Methoxy Amodimethicone/Silsesquioxane Copolymer functions as: Film forming, hair conditioning, skin conditioning.. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (polymer). COSING Ref No: 57950, PCPC No: 16775..

What is the Margin of Safety for Methoxy Amodimethicone/Silsesquioxane Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Methoxy Amodimethicone/Silsesquioxane Copolymer compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Hordeum Vulgare Leaf Juice
Poor
RESVERATRYL TRIGLYCOLATE
Good
Ajuga Turkestanica Flower Extract
Moderate
Dihydrogenated Palmoyl Hydroxyethylmonium Methosulfate
Good
Deoxyphytantriyl Palmitamide MEA
Good
Browse all 30,000+ ingredients →
📱

Is Methoxy Amodimethicone/Silsesquioxane Copolymer in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methoxy Amodimethicone/Silsesquioxane Copolymer in your formulation.

Ingredient Decoder MoS Calculator