Methoxy-Methylbutanethiol

INCI: METHOXY-METHYLBUTANETHIOL

CAS Number
Not explicitly listed in CosIng/COSMILE entries; PubChem lists the compound 4-Methoxy-2-methylbutanethiol under CID 87289881
Function
Fragrance
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not specifically prohibited; fragrance use regulated via IFRA/RIFM

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Thiol-containing compounds can have strong odor profiles even at trace levels; potential skin sensitization per general fragrance allergen principles. Contains a sulfur (thiol) functional group, which typically imparts potent, character-defining notes (often fruity/tropical at low doses). Related isopropyl methylcyclohexene thiols are documented as grapefruit/tropical/blackcurrant notes

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Methoxy-Methylbutanethiol safe in cosmetics?

Thiol-containing compounds can have strong odor profiles even at trace levels; potential skin sensitization per general fragrance allergen principles. Contains a sulfur (thiol) functional group, which typically imparts potent, character-defining notes (often fruity/tropical at low doses). Related isopropyl methylcyclohexene thiols are documented as grapefruit/tropical/blackcurrant notes The EU classifies Methoxy-Methylbutanethiol as "permitted". Safety rating: MODERATE.

Is Methoxy-Methylbutanethiol allowed in the EU?

Methoxy-Methylbutanethiol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy-Methylbutanethiol do in cosmetics?

Methoxy-Methylbutanethiol functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: Not explicitly listed in CosIng/COSMILE entries; PubChem lists the compound 4-Methoxy-2-methylbutanethiol under CID 87289881.

What is the Margin of Safety for Methoxy-Methylbutanethiol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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