Moderate Cosmetic Ingredient

Methoxy PEG-10 Polysilsesquioxane

INCI: METHOXY PEG-10 POLYSILSESQUIOXANE

CAS Number
Not publicly assigned (polymer). A related ingredient, Isobutyl/Methoxy PEG-10 Polysilsesquioxane, is listed in CosIng as viscosity controlling.
Function
Surface modification, viscosity controlling. Used as a hydrophilic modifier in silsesquioxane systems.
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed; not specifically prohibited or restricted. CIR reviewed polysilsesquioxane ingredients including this one.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low toxicity profile based on CIR review of polysilsesquioxanes. Acute oral toxicity data available for related Isobutyl/Methoxy PEG-10 Polysilsesquioxane. Standard PEG contamination concerns apply.. Cage-structure organosilicon polymer with PEG-modified arms providing hydrophilicity; used to surface-treat pigments for improved dispersibility in aqueous/emulsion systems.

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Concern Level: High

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-10 Polysilsesquioxane safe in cosmetics?

Low toxicity profile based on CIR review of polysilsesquioxanes. Acute oral toxicity data available for related Isobutyl/Methoxy PEG-10 Polysilsesquioxane. Standard PEG contamination concerns apply.. Cage-structure organosilicon polymer with PEG-modified arms providing hydrophilicity; used to surface-treat pigments for improved dispersibility in aqueous/emulsion systems. The EU classifies Methoxy PEG-10 Polysilsesquioxane as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-10 Polysilsesquioxane allowed in the EU?

Methoxy PEG-10 Polysilsesquioxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-10 Polysilsesquioxane do in cosmetics?

Methoxy PEG-10 Polysilsesquioxane functions as: Surface modification, viscosity controlling. Used as a hydrophilic modifier in silsesquioxane systems.. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (polymer). A related ingredient, Isobutyl/Methoxy PEG-10 Polysilsesquioxane, is listed in CosIng as viscosity controlling..

What is the Margin of Safety for Methoxy PEG-10 Polysilsesquioxane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Methoxy PEG-10 Polysilsesquioxane compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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