Methoxy PEG-100/Polyepsilon Caprolactone

INCI: METHOXY PEG-100/POLYEPSILON CAPROLACTONE (NOTE: A RELATED COSING ENTRY IS METHOXY PEG-100/POLYEPSILON CAPROLACTONE PALMITATE, REF 89425).

CAS Number
Many cosmetic polymers and copolymers (especially silsesquioxanes and PEG-caprolactone block copolymers) do not have registered CAS numbers - they are identified by INCI name and COSING reference instead.
Function
Film forming, skin conditioning, emulsifying. Amphiphilic diblock copolymer.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed; not specifically prohibited or restricted.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Similar to #9 - biodegradable copolymer with low irritation potential. PEG-related impurity concerns apply. Polycaprolactone is FDA-approved for medical device use, supporting its biocompatibility profile.. Diblock copolymer architecture (hydrophilic PEG block + hydrophobic polycaprolactone block) enables self-assembly into nanocarriers; widely studied in pharmaceutical and cosmetic delivery for encapsulation of actives; biodegradable and biocompatible.

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-100/Polyepsilon Caprolactone safe in cosmetics?

Similar to #9 - biodegradable copolymer with low irritation potential. PEG-related impurity concerns apply. Polycaprolactone is FDA-approved for medical device use, supporting its biocompatibility profile.. Diblock copolymer architecture (hydrophilic PEG block + hydrophobic polycaprolactone block) enables self-assembly into nanocarriers; widely studied in pharmaceutical and cosmetic delivery for encapsulation of actives; biodegradable and biocompatible. The EU classifies Methoxy PEG-100/Polyepsilon Caprolactone as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-100/Polyepsilon Caprolactone allowed in the EU?

Methoxy PEG-100/Polyepsilon Caprolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-100/Polyepsilon Caprolactone do in cosmetics?

Methoxy PEG-100/Polyepsilon Caprolactone functions as: Film forming, skin conditioning, emulsifying. Amphiphilic diblock copolymer.. It is classified as a cosmetic ingredient in our database. CAS number: Many cosmetic polymers and copolymers (especially silsesquioxanes and PEG-caprolactone block copolymers) do not have registered CAS numbers - they are identified by INCI name and COSING reference instead..

What is the Margin of Safety for Methoxy PEG-100/Polyepsilon Caprolactone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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