Moderate Cosmetic Ingredient

Methoxy PEG-25

INCI: METHOXY PEG-25

CAS Number
Not confirmed from available databases; likely falls under polyethylene glycol monomethyl ether series (general CAS 9004-74-4 covers mPEG of various MW) - verify before using in regulatory filings
Function
Solvent, humectant (consistent with standard mPEG functions for liquid-range PEGs)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not prohibited; no specific CIR monograph dedicated to this exact ingredient identified

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Standard PEG-class concerns: potential 1,4-dioxane contamination from ethoxylation; may enhance skin penetration of other ingredients. With ~25 EO units, this falls in the liquid-to-waxy range (~1,100 g/mol); water-soluble, non-greasy; functions as a glycerol substitute in lotions

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG-25 safe in cosmetics?

Standard PEG-class concerns: potential 1,4-dioxane contamination from ethoxylation; may enhance skin penetration of other ingredients. With ~25 EO units, this falls in the liquid-to-waxy range (~1,100 g/mol); water-soluble, non-greasy; functions as a glycerol substitute in lotions The EU classifies Methoxy PEG-25 as "permitted". Safety rating: MODERATE.

Is Methoxy PEG-25 allowed in the EU?

Methoxy PEG-25 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG-25 do in cosmetics?

Methoxy PEG-25 functions as: Solvent, humectant (consistent with standard mPEG functions for liquid-range PEGs). It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from available databases; likely falls under polyethylene glycol monomethyl ether series (general CAS 9004-74-4 covers mPEG of various MW) - verify before using in regulatory filings.

What is the Margin of Safety for Methoxy PEG-25?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Methoxy PEG-25 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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