Methoxy PEG/PPG-25/4 Dimethicone

INCI: METHOXY PEG/PPG-25/4 DIMETHICONE

CAS Number
Not individually registered in major CAS databases (proprietary silicone-PEG/PPG copolymer)
Function
Emulsifying (surfactant), emulsion stabilising
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted; dimethicone copolyols are broadly permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EWG rating of 3 (acceptable); silicone backbone is biologically inert; PEG/PPG chains carry 1,4-dioxane trace concern; generally well-tolerated. Alkoxylated dimethicone with 25 EO and 4 PO units; the PEG/PPG ratio tunes HLB for versatile emulsification; provides silicone-characteristic slip and spreadability alongside emulsification capability

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Concern Level: Moderate

Regulatory Flags

peg-ingredient

Frequently Asked Questions

Is Methoxy PEG/PPG-25/4 Dimethicone safe in cosmetics?

EWG rating of 3 (acceptable); silicone backbone is biologically inert; PEG/PPG chains carry 1,4-dioxane trace concern; generally well-tolerated. Alkoxylated dimethicone with 25 EO and 4 PO units; the PEG/PPG ratio tunes HLB for versatile emulsification; provides silicone-characteristic slip and spreadability alongside emulsification capability The EU classifies Methoxy PEG/PPG-25/4 Dimethicone as "permitted". Safety rating: MODERATE.

Is Methoxy PEG/PPG-25/4 Dimethicone allowed in the EU?

Methoxy PEG/PPG-25/4 Dimethicone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methoxy PEG/PPG-25/4 Dimethicone do in cosmetics?

Methoxy PEG/PPG-25/4 Dimethicone functions as: Emulsifying (surfactant), emulsion stabilising. It is classified as a cosmetic ingredient in our database. CAS number: Not individually registered in major CAS databases (proprietary silicone-PEG/PPG copolymer).

What is the Margin of Safety for Methoxy PEG/PPG-25/4 Dimethicone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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