Methyl Coco-Glucosides

INCI: METHYL COCO-GLUCOSIDES

CAS Number
Not confirmed in open databases — methylated derivative of coco-glucoside (CAS 110615-47-9 for parent APG)
Function
Surfactant; cleansing; emulsifying (by analogy with alkyl polyglucosides)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mild primary irritant at 100% concentration in rabbits; formulations at typical use concentrations (≤24%) classified as non-irritating and non-sensitizing. Ames test negative with no tumor promotion observed in animal models. Read-across from decyl glucoside and coco-glucoside CIR monograph is defensible.

⚠️
Concern Level: Low

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Methyl Coco-Glucosides safe in cosmetics?

Mild primary irritant at 100% concentration in rabbits; formulations at typical use concentrations (≤24%) classified as non-irritating and non-sensitizing. Ames test negative with no tumor promotion observed in animal models. Read-across from decyl glucoside and coco-glucoside CIR monograph is defensible. The EU classifies Methyl Coco-Glucosides as "permitted". Safety rating: GOOD.

Is Methyl Coco-Glucosides allowed in the EU?

Methyl Coco-Glucosides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Coco-Glucosides do in cosmetics?

Methyl Coco-Glucosides functions as: Surfactant; cleansing; emulsifying (by analogy with alkyl polyglucosides). It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in open databases — methylated derivative of coco-glucoside (CAS 110615-47-9 for parent APG).

What is the Margin of Safety for Methyl Coco-Glucosides?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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