Methyl Isostearate

INCI: METHYL ISOSTEARATE

CAS Number
5129-61-3
Function
Emollient, skin conditioning agent, emulsifier
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally considered safe; low irritation and sensitization potential; CIR reviewed the broader isostearate family. Branched-chain C19 fatty acid methyl ester (methyl 16-methylheptadecanoate); branching imparts excellent spreadability, a light non-greasy feel, and enhanced oxidative stability compared to straight-chain esters; improves skin texture and hydration

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Methyl Isostearate safe in cosmetics?

Generally considered safe; low irritation and sensitization potential; CIR reviewed the broader isostearate family. Branched-chain C19 fatty acid methyl ester (methyl 16-methylheptadecanoate); branching imparts excellent spreadability, a light non-greasy feel, and enhanced oxidative stability compared to straight-chain esters; improves skin texture and hydration The EU classifies Methyl Isostearate as "permitted". Safety rating: MODERATE.

Is Methyl Isostearate allowed in the EU?

Methyl Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Isostearate do in cosmetics?

Methyl Isostearate functions as: Emollient, skin conditioning agent, emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 5129-61-3.

What is the Margin of Safety for Methyl Isostearate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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