Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Generally considered safe; as a naturally occurring metabolite of niacinamide (vitamin B3), it has a favorable safety profile. Manufacturers must follow local regulations for use concentrations. Also known as 1-Methylnicotinamide (1-MNA); a natural metabolite of niacinamide produced endogenously in the body. Emerging active ingredient that complements niacinamide in formulations, with research suggesting anti-inflammatory and vascular-protective benefits. Gaining traction as a novel cosmetic ...
Regulatory Flags
Frequently Asked Questions
Is Methyl Niacinamide Chloride safe in cosmetics?
Generally considered safe; as a naturally occurring metabolite of niacinamide (vitamin B3), it has a favorable safety profile. Manufacturers must follow local regulations for use concentrations. Also known as 1-Methylnicotinamide (1-MNA); a natural metabolite of niacinamide produced endogenously in the body. Emerging active ingredient that complements niacinamide in formulations, with research suggesting anti-inflammatory and vascular-protective benefits. Gaining traction as a novel cosmetic ... The EU classifies Methyl Niacinamide Chloride as "permitted". Safety rating: MODERATE.
Is Methyl Niacinamide Chloride allowed in the EU?
Methyl Niacinamide Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Niacinamide Chloride do in cosmetics?
Methyl Niacinamide Chloride functions as: Skin conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 1005-24-9.
What is the Margin of Safety for Methyl Niacinamide Chloride?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Methyl Niacinamide Chloride compliance across multiple jurisdictions:
Related Ingredients
Is Methyl Niacinamide Chloride in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methyl Niacinamide Chloride in your formulation.