Methyl Tyrosinate HCl

INCI: METHYL TYROSINATE HCL

CAS Number
3417-91-2 (L-Tyrosine methyl ester hydrochloride)
Function
Skin conditioning agent; may also function as a melanin synthesis modulator (tyrosine is a melanin precursor)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low toxicity profile for topical use; theoretical concern regarding melanogenesis stimulation - products claiming to accelerate tanning via tyrosine derivatives should be assessed for efficacy claims vs. cosmetic classification.. Amino acid ester derivative; tyrosine is the starting substrate for melanin biosynthesis, so derivatives may be marketed for tanning support; better skin penetration than free tyrosine due to ester form.

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Concern Level: High

Frequently Asked Questions

Is Methyl Tyrosinate HCl safe in cosmetics?

Low toxicity profile for topical use; theoretical concern regarding melanogenesis stimulation - products claiming to accelerate tanning via tyrosine derivatives should be assessed for efficacy claims vs. cosmetic classification.. Amino acid ester derivative; tyrosine is the starting substrate for melanin biosynthesis, so derivatives may be marketed for tanning support; better skin penetration than free tyrosine due to ester form. The EU classifies Methyl Tyrosinate HCl as "permitted". Safety rating: MODERATE.

Is Methyl Tyrosinate HCl allowed in the EU?

Methyl Tyrosinate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Tyrosinate HCl do in cosmetics?

Methyl Tyrosinate HCl functions as: Skin conditioning agent; may also function as a melanin synthesis modulator (tyrosine is a melanin precursor). It is classified as a cosmetic ingredient in our database. CAS number: 3417-91-2 (L-Tyrosine methyl ester hydrochloride).

What is the Margin of Safety for Methyl Tyrosinate HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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