Moderate Cosmetic Ingredient NOAEL Data

Methyl Undecenoate

INCI: METHYL UNDECYLENATE (COSING)

CAS Number
111-81-9
Function
Skin conditioning agent; antifungal properties (undecylenic acid derivatives are known antifungals)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition. Undecylenic acid and derivatives are recognized as OTC antifungal actives, but the methyl ester in cosmetic use is classified as a cosmetic ingredient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Methyl Undecenoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 60 mg/kg bw/day oral rat oral REACH

Expert Verdict

Generally low irritation potential; undecylenic acid derivatives have a long history of safe use.. Chemical name: methyl 10-undecenoate; contains a terminal double bond providing reactivity for further chemistry; mild characteristic odor; derived from castor oil.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Methyl Undecenoate safe in cosmetics?

Generally low irritation potential; undecylenic acid derivatives have a long history of safe use.. Chemical name: methyl 10-undecenoate; contains a terminal double bond providing reactivity for further chemistry; mild characteristic odor; derived from castor oil. The EU classifies Methyl Undecenoate as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Methyl Undecenoate allowed in the EU?

Methyl Undecenoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Undecenoate do in cosmetics?

Methyl Undecenoate functions as: Skin conditioning agent; antifungal properties (undecylenic acid derivatives are known antifungals). It is classified as a cosmetic ingredient in our database. CAS number: 111-81-9.

What is the Margin of Safety for Methyl Undecenoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Methyl Undecenoate?

The NOAEL (No Observed Adverse Effect Level) for Methyl Undecenoate is 60 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

๐Ÿ“ฑ

Is Methyl Undecenoate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methyl Undecenoate in your formulation.