Methylenedioxyphenylsuccinoyl Nonapeptide-18

INCI: METHYLENEDIOXYPHENYLSUCCINOYL NONAPEPTIDE-18

CAS Number
Not widely listed; proprietary peptide ingredient
Function
Skin conditioning (anti-aging/skin-brightening peptide)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Similar safety profile to other cosmetic peptides; generally considered safe at recommended use levels; limited independent published data typical of proprietary peptides. A nonapeptide (9 amino acids) conjugated with the same methylenedioxyphenylsuccinoyl carrier as ingredient #7; the longer peptide chain likely targets a different biological mechanism (e.g., melanogenesis modulation or extracellular matrix support); the conjugation strategy mirrors modern peptidomimetic design for improved ...

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Concern Level: Moderate

Frequently Asked Questions

Is Methylenedioxyphenylsuccinoyl Nonapeptide-18 safe in cosmetics?

Similar safety profile to other cosmetic peptides; generally considered safe at recommended use levels; limited independent published data typical of proprietary peptides. A nonapeptide (9 amino acids) conjugated with the same methylenedioxyphenylsuccinoyl carrier as ingredient #7; the longer peptide chain likely targets a different biological mechanism (e.g., melanogenesis modulation or extracellular matrix support); the conjugation strategy mirrors modern peptidomimetic design for improved ... The EU classifies Methylenedioxyphenylsuccinoyl Nonapeptide-18 as "permitted". Safety rating: MODERATE.

Is Methylenedioxyphenylsuccinoyl Nonapeptide-18 allowed in the EU?

Methylenedioxyphenylsuccinoyl Nonapeptide-18 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylenedioxyphenylsuccinoyl Nonapeptide-18 do in cosmetics?

Methylenedioxyphenylsuccinoyl Nonapeptide-18 functions as: Skin conditioning (anti-aging/skin-brightening peptide). It is classified as a cosmetic ingredient in our database. CAS number: Not widely listed; proprietary peptide ingredient.

What is the Margin of Safety for Methylenedioxyphenylsuccinoyl Nonapeptide-18?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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