Methylmethionine

INCI: METHYLMETHIONINE

CAS Number
4727-40-6
Function
Astringent, Oral Care, Skin Conditioning, Skin Conditioning - Emollient, Skin Protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No documented cosmetic safety concerns; the compound is a naturally occurring amino acid derivative. Chemically described as sulfonium, [(3S)-3-amino-3-carboxypropyl]dimethyl-, inner salt; widely known as Vitamin U (S-methylmethionine); naturally found in cabbage and other cruciferous vegetables; valued for wound-healing support, anti-inflammatory action, and mucosal protection - hence the oral care function

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Methylmethionine safe in cosmetics?

No documented cosmetic safety concerns; the compound is a naturally occurring amino acid derivative. Chemically described as sulfonium, [(3S)-3-amino-3-carboxypropyl]dimethyl-, inner salt; widely known as Vitamin U (S-methylmethionine); naturally found in cabbage and other cruciferous vegetables; valued for wound-healing support, anti-inflammatory action, and mucosal protection - hence the oral care function The EU classifies Methylmethionine as "permitted". Safety rating: MODERATE.

Is Methylmethionine allowed in the EU?

Methylmethionine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylmethionine do in cosmetics?

Methylmethionine functions as: Astringent, Oral Care, Skin Conditioning, Skin Conditioning - Emollient, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 4727-40-6.

What is the Margin of Safety for Methylmethionine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Methylmethionine in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Methylmethionine in your formulation.