Methylsilanol Hydroxyproline

INCI: METHYLSILANOL HYDROXYPROLINE

CAS Number
Not confirmed in public databases (Exsymol proprietary; trade name: Hydroxyprolisilane C/CN)
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” hydroxyproline is an endogenous amino acid; no CFR restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydroxyproline is endogenous and non-toxic; the methylsilanol carrier is the primary variable with low intrinsic toxicity expected and longest market history in this family.

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Concern Level: Low

Frequently Asked Questions

Is Methylsilanol Hydroxyproline safe in cosmetics?

Hydroxyproline is endogenous and non-toxic; the methylsilanol carrier is the primary variable with low intrinsic toxicity expected and longest market history in this family. The EU classifies Methylsilanol Hydroxyproline as "permitted". Safety rating: GOOD.

Is Methylsilanol Hydroxyproline allowed in the EU?

Methylsilanol Hydroxyproline EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylsilanol Hydroxyproline do in cosmetics?

Methylsilanol Hydroxyproline functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in public databases (Exsymol proprietary; trade name: Hydroxyprolisilane C/CN).

What is the Margin of Safety for Methylsilanol Hydroxyproline?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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