Methylsilanol PCA

INCI: METHYLSILANOL PCA

CAS Number
105883-41-8
Function
Skin conditioning, humectant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” PCA (pyrrolidone carboxylic acid) is endogenous (NMF component); no CFR restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PCA is a natural component of the skin's Natural Moisturizing Factor (NMF); classified as acceptable in independent ingredient databases with minimal concern profile.

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Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Methylsilanol PCA safe in cosmetics?

PCA is a natural component of the skin's Natural Moisturizing Factor (NMF); classified as acceptable in independent ingredient databases with minimal concern profile. The EU classifies Methylsilanol PCA as "permitted". Safety rating: GOOD.

Is Methylsilanol PCA allowed in the EU?

Methylsilanol PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylsilanol PCA do in cosmetics?

Methylsilanol PCA functions as: Skin conditioning, humectant. It is classified as a cosmetic ingredient in our database. CAS number: 105883-41-8.

What is the Margin of Safety for Methylsilanol PCA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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