Methylspermidine

INCI: METHYLSPERMIDINE

CAS Number
Not specifically assigned in publicly accessible CosIng records; the related compound 1-methylspermidine is referenced in PubChem
Function
Hair conditioning - leaves hair easy to comb, supple, soft, shiny, and/or imparts volume
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited or restricted; falls under the general "allowed" category for cosmetic ingredients under FD&C Act provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited publicly available safety/toxicology data; as a polyamine derivative, potential irritation at high concentrations should be evaluated. Derived from spermidine, a naturally occurring polyamine; a patent describes N-methylspermidine as an active ingredient for combating alopecia (hair loss)

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Concern Level: High

Frequently Asked Questions

Is Methylspermidine safe in cosmetics?

Limited publicly available safety/toxicology data; as a polyamine derivative, potential irritation at high concentrations should be evaluated. Derived from spermidine, a naturally occurring polyamine; a patent describes N-methylspermidine as an active ingredient for combating alopecia (hair loss) The EU classifies Methylspermidine as "restricted". Safety rating: MODERATE.

Is Methylspermidine allowed in the EU?

Methylspermidine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Methylspermidine do in cosmetics?

Methylspermidine functions as: Hair conditioning - leaves hair easy to comb, supple, soft, shiny, and/or imparts volume. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned in publicly accessible CosIng records; the related compound 1-methylspermidine is referenced in PubChem.

What is the Margin of Safety for Methylspermidine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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