Regulatory Status
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Safety Data
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Expert Verdict
Mevalonolactone is the lactone (cyclic ester) form of mevalonic acid, a naturally occurring intermediate in the mevalonate pathway (cholesterol biosynthesis). Generally considered low-risk due to its endogenous biochemistry. Limited published cosmetic-specific toxicological data. Precursor to mevalonic acid upon hydrolysis; supports cutaneous lipid synthesis and skin barrier repair. Used as the reactive moiety to produce mevalonoyl-conjugated peptides
Regulatory Flags
Frequently Asked Questions
Is Mevalonolactone safe in cosmetics?
Mevalonolactone is the lactone (cyclic ester) form of mevalonic acid, a naturally occurring intermediate in the mevalonate pathway (cholesterol biosynthesis). Generally considered low-risk due to its endogenous biochemistry. Limited published cosmetic-specific toxicological data. Precursor to mevalonic acid upon hydrolysis; supports cutaneous lipid synthesis and skin barrier repair. Used as the reactive moiety to produce mevalonoyl-conjugated peptides The EU classifies Mevalonolactone as "permitted". Safety rating: MODERATE.
Is Mevalonolactone allowed in the EU?
Mevalonolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Mevalonolactone do in cosmetics?
Mevalonolactone functions as: Skin-conditioning agent, humectant. It is classified as a cosmetic ingredient in our database. CAS number: 674-26-0.
What is the Margin of Safety for Mevalonolactone?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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