Mevalonoyl Pentapeptide-39

INCI: MEVALONOYL PENTAPEPTIDE-39

CAS Number
Not publicly assigned
Function
Skin conditioning agent (anticipated from peptide class and INCI conventions)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited published safety data. As a mevalonoyl-conjugated pentapeptide, safety is extrapolated from the general mevalonoyl peptide class. No dedicated CIR or SCCS evaluation. Registered in the Korean Cosmetic Ingredient Dictionary (KCIA). Product of reaction of mevalonic acid with Pentapeptide-39. Part of the growing class of lipopeptide conjugates designed for enhanced skin penetration and bioactivity

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Concern Level: Moderate

Frequently Asked Questions

Is Mevalonoyl Pentapeptide-39 safe in cosmetics?

Very limited published safety data. As a mevalonoyl-conjugated pentapeptide, safety is extrapolated from the general mevalonoyl peptide class. No dedicated CIR or SCCS evaluation. Registered in the Korean Cosmetic Ingredient Dictionary (KCIA). Product of reaction of mevalonic acid with Pentapeptide-39. Part of the growing class of lipopeptide conjugates designed for enhanced skin penetration and bioactivity The EU classifies Mevalonoyl Pentapeptide-39 as "permitted". Safety rating: MODERATE.

Is Mevalonoyl Pentapeptide-39 allowed in the EU?

Mevalonoyl Pentapeptide-39 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mevalonoyl Pentapeptide-39 do in cosmetics?

Mevalonoyl Pentapeptide-39 functions as: Skin conditioning agent (anticipated from peptide class and INCI conventions). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for Mevalonoyl Pentapeptide-39?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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