Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40

INCI: MICROBIAL CELLULOSE/SR-SPIDER POLYPEPTIDE-3 HEXAPEPTIDE-40

CAS Number
No single CAS assigned (complex hybrid ingredient)
Function
Emollient, humectant, occlusive; anti-aging (anti-wrinkle, antioxidant), moisture protection
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not listed as prohibited or restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Described as hypoallergenic, biocompatible, and biodegradable; no significant safety flags reported. A recombinant spider silk protein produced via E. coli fermentation, combined with microbial cellulose to form a semi-permeable film for moisture protection. Recommended dosage is 0.005%-0.025%. It stimulates collagen synthesis and moisture-related gene expression

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 safe in cosmetics?

Described as hypoallergenic, biocompatible, and biodegradable; no significant safety flags reported. A recombinant spider silk protein produced via E. coli fermentation, combined with microbial cellulose to form a semi-permeable film for moisture protection. Recommended dosage is 0.005%-0.025%. It stimulates collagen synthesis and moisture-related gene expression The EU classifies Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 as "permitted". Safety rating: MODERATE.

Is Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 allowed in the EU?

Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 do in cosmetics?

Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40 functions as: Emollient, humectant, occlusive; anti-aging (anti-wrinkle, antioxidant), moisture protection. It is classified as a cosmetic ingredient in our database. CAS number: No single CAS assigned (complex hybrid ingredient).

What is the Margin of Safety for Microbial Cellulose/SR-Spider Polypeptide-3 Hexapeptide-40?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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