Milkamidopropyl Amine Oxide

INCI: MILKAMIDOPROPYL AMINE OXIDE

CAS Number
Not uniquely assigned (structural analogue of cocamidopropyl amine oxide, CAS 68155-09-9, derived from milk fatty acids instead of coconut)
Function
Surfactant — cleansing, foam boosting, hair conditioning, skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restrictions; CIR reviewed alkyl amide MIPA analogues as safe

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

DMAPA (3-dimethylaminopropylamine) impurity is a known contact sensitizer — must be controlled to <0.01%; irritation potential at concentrations >4%; rinse-off use preferred

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Milkamidopropyl Amine Oxide safe in cosmetics?

DMAPA (3-dimethylaminopropylamine) impurity is a known contact sensitizer — must be controlled to <0.01%; irritation potential at concentrations >4%; rinse-off use preferred The EU classifies Milkamidopropyl Amine Oxide as "permitted". Safety rating: GOOD.

Is Milkamidopropyl Amine Oxide allowed in the EU?

Milkamidopropyl Amine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Milkamidopropyl Amine Oxide do in cosmetics?

Milkamidopropyl Amine Oxide functions as: Surfactant — cleansing, foam boosting, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (structural analogue of cocamidopropyl amine oxide, CAS 68155-09-9, derived from milk fatty acids instead of coconut).

What is the Margin of Safety for Milkamidopropyl Amine Oxide?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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