Minoxapol 742

INCI: MINOXAPOL 742

CAS Number
Not uniquely assigned (falls under broad poloxamine/block copolymer CAS groupings)
Function
Surfactant, emulsifier, solubilizer
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - block copolymer surfactants are generally permitted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Low toxicity; non-ionic block copolymer; may contain residual ethylene oxide/propylene oxide. "Minoxapol" is the reverse of "Poloxamine" - the structure is [(PPG)ₓ-(PEG)ᵧ]₂-NCH₂CH₂N-[(PEG)ᵧ-(PPG)ₓ]₂ (PPG block exterior, PEG block interior), which is the inverse architecture of poloxamine. The numerical suffix 742 encodes the molecular weight and PEG/PPG ratio. This is a synthetic, non-animal-derived ingredient.

⚠️
Concern Level: High

Frequently Asked Questions

Is Minoxapol 742 safe in cosmetics?

Low toxicity; non-ionic block copolymer; may contain residual ethylene oxide/propylene oxide. "Minoxapol" is the reverse of "Poloxamine" - the structure is [(PPG)ₓ-(PEG)ᵧ]₂-NCH₂CH₂N-[(PEG)ᵧ-(PPG)ₓ]₂ (PPG block exterior, PEG block interior), which is the inverse architecture of poloxamine. The numerical suffix 742 encodes the molecular weight and PEG/PPG ratio. This is a synthetic, non-animal-derived ingredient. The EU classifies Minoxapol 742 as "permitted". Safety rating: MODERATE.

Is Minoxapol 742 allowed in the EU?

Minoxapol 742 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Minoxapol 742 do in cosmetics?

Minoxapol 742 functions as: Surfactant, emulsifier, solubilizer. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (falls under broad poloxamine/block copolymer CAS groupings).

What is the Margin of Safety for Minoxapol 742?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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