Mitoquinol Mesylate

INCI: MITOQUINOL MESYLATE

CAS Number
845959-55-9
Function
Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed in cosmetics; not prohibited or restricted. Also investigated as a pharmaceutical (MitoQ) at Phase 2/3 clinical trials for various conditions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

As a mitochondria-targeted antioxidant, it is a potent bioactive. Designated an Orphan Drug in the US for pharmaceutical applications. Long-term topical safety data in cosmetics are limited. This is the cosmetic-grade form of MitoQ (mitoquinone mesylate), a triphenylphosphonium-conjugated ubiquinone derivative that selectively accumulates in mitochondria, providing targeted antioxidant protection at the cellular level

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Concern Level: Moderate

Frequently Asked Questions

Is Mitoquinol Mesylate safe in cosmetics?

As a mitochondria-targeted antioxidant, it is a potent bioactive. Designated an Orphan Drug in the US for pharmaceutical applications. Long-term topical safety data in cosmetics are limited. This is the cosmetic-grade form of MitoQ (mitoquinone mesylate), a triphenylphosphonium-conjugated ubiquinone derivative that selectively accumulates in mitochondria, providing targeted antioxidant protection at the cellular level The EU classifies Mitoquinol Mesylate as "permitted". Safety rating: MODERATE.

Is Mitoquinol Mesylate allowed in the EU?

Mitoquinol Mesylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Mitoquinol Mesylate do in cosmetics?

Mitoquinol Mesylate functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 845959-55-9.

What is the Margin of Safety for Mitoquinol Mesylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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