Octahydro-trimethyl-ethano-naphthoxirene
INCI: OCTAHYDRO-TRIMETHYL-ETHANO-NAPHTHOXIRENE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
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Expert Verdict
CRITICAL — EPOXIDE STRUCTURAL ALERT. Naphthoxirene = naphthalene-fused oxirane. Epoxides are electrophilic, protein-reactive, and flagged for both genotoxicity and skin sensitisation. ECHA C&L notifications for related naphthoxirenes include H315 (skin irritation) and H411 (aquatic chronic toxicity). Mandatory testing before inclusion: Ames test, in-vitro micronucleus, DPRA, KeratinoSens, h-CLAT. Do NOT include in any CPSR without complete genotoxicity and sensitisation data.
Frequently Asked Questions
Is Octahydro-trimethyl-ethano-naphthoxirene safe in cosmetics?
CRITICAL — EPOXIDE STRUCTURAL ALERT. Naphthoxirene = naphthalene-fused oxirane. Epoxides are electrophilic, protein-reactive, and flagged for both genotoxicity and skin sensitisation. ECHA C&L notifications for related naphthoxirenes include H315 (skin irritation) and H411 (aquatic chronic toxicity). Mandatory testing before inclusion: Ames test, in-vitro micronucleus, DPRA, KeratinoSens, h-CLAT. Do NOT include in any CPSR without complete genotoxicity and sensitisation data. The EU classifies Octahydro-trimethyl-ethano-naphthoxirene as "permitted". Safety rating: POOR.
Is Octahydro-trimethyl-ethano-naphthoxirene allowed in the EU?
Octahydro-trimethyl-ethano-naphthoxirene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Octahydro-trimethyl-ethano-naphthoxirene do in cosmetics?
Octahydro-trimethyl-ethano-naphthoxirene functions as: Standalone Tox Data. It is classified as a cosmetic ingredient in our database. CAS number: † Verify via CosIng (sesquiterpene epoxide; structurally related to PubChem CID 11264493).
What is the Margin of Safety for Octahydro-trimethyl-ethano-naphthoxirene?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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