Octoxynol-9

INCI: OCTOXYNOL-9

CAS Number
9
Function
Surfactant - emulsifying, cleansing; fragrance functional
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes 10

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Known spermicidal activity at high concentrations with acute oral LD50 >1 g/kg in rats; CIR 2023 re-review triggered for use in baby products at 0.1%; inhalation exposure at high doses caused pneumonia and edema in hamsters; contains residual ethylene oxide and 1,4-dioxane; generates environmental endocrine disruptor degradation products; not eligible for COSMOS or ECOCERT certification.

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Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Octoxynol-9 safe in cosmetics?

Known spermicidal activity at high concentrations with acute oral LD50 >1 g/kg in rats; CIR 2023 re-review triggered for use in baby products at 0.1%; inhalation exposure at high doses caused pneumonia and edema in hamsters; contains residual ethylene oxide and 1,4-dioxane; generates environmental endocrine disruptor degradation products; not eligible for COSMOS or ECOCERT certification. The EU classifies Octoxynol-9 as "permitted". Safety rating: GOOD.

Is Octoxynol-9 allowed in the EU?

Octoxynol-9 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Octoxynol-9 do in cosmetics?

Octoxynol-9 functions as: Surfactant - emulsifying, cleansing; fragrance functional. It is classified as a cosmetic ingredient in our database. CAS number: 9.

What is the Margin of Safety for Octoxynol-9?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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