Good Cosmetic Ingredient NOAEL Data

P-METHYL ACETOPHENONE

CAS Number
122-00-9
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for P-METHYL ACETOPHENONE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 100000 ppm oral rat oral REACH
NOAEL 225 mg/kg bw/day oral rat oral REACH

Expert Verdict

P-METHYL ACETOPHENONE is listed in the EU CosIng database with functions: Fragrance It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment ifra_fragrance fda_food_additive

Frequently Asked Questions

Is P-METHYL ACETOPHENONE safe in cosmetics?

P-METHYL ACETOPHENONE is listed in the EU CosIng database with functions: Fragrance It is permitted in the EU without specific restrictions. The EU classifies P-METHYL ACETOPHENONE as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is P-METHYL ACETOPHENONE allowed in the EU?

P-METHYL ACETOPHENONE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does P-METHYL ACETOPHENONE do in cosmetics?

P-METHYL ACETOPHENONE functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 122-00-9.

What is the NOAEL for P-METHYL ACETOPHENONE?

The NOAEL (No Observed Adverse Effect Level) for P-METHYL ACETOPHENONE is 100000 ppm based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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