Moderate Cosmetic Ingredient GHS Classified

P-PHENYLENEDIAMINE HCL

CAS Number
624-18-0
Function
Hair Dyeing
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status Restricted
EU Max Conc. III/8a
🇺🇸 US Status permitted
US Notes CIR: S - IJT 32(Suppl. 4):41-64, 2013

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes. The substance may cause effects on the blood and kidneys. This may result in the formation of methaemoglobin and kidney impairment. Medical observation is indicated. The effects may be delayed.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Expert Verdict

P-PHENYLENEDIAMINE HCL is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/8a.

⚠️
Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment

Frequently Asked Questions

Is P-PHENYLENEDIAMINE HCL safe in cosmetics?

P-PHENYLENEDIAMINE HCL is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/8a. The EU classifies P-PHENYLENEDIAMINE HCL as "Restricted". Safety rating: MODERATE.

Is P-PHENYLENEDIAMINE HCL allowed in the EU?

P-PHENYLENEDIAMINE HCL EU regulatory status: Restricted. Maximum allowed concentration: III/8a. This is based on EU Regulation 1223/2009 and its amendments.

What does P-PHENYLENEDIAMINE HCL do in cosmetics?

P-PHENYLENEDIAMINE HCL functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 624-18-0.

Compliance Tools

Check P-PHENYLENEDIAMINE HCL compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

COCHINEAL
Moderate
P-METHYLAMINOPHENOL
Moderate
NITROPHENOL
Good
4,5-DIAMINO-1-((4-CHLOROPHENYL)METHYL)-1H-PYRAZOLE-SULFATE
Moderate
N,N-DIETHYL-M-AMINOPHENOL SULFATE
Moderate
Browse all 30,000+ ingredients →
📱

Is P-PHENYLENEDIAMINE HCL in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for P-PHENYLENEDIAMINE HCL in your formulation.

Ingredient Decoder MoS Calculator