Is PEG-2 CAPRYLYLAMINE safe in cosmetics?
PEG-2 CAPRYLYLAMINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed. 1 toxicological study endpoint(s) are available in our database.
PEG-2 CAPRYLYLAMINE
Also known as: Ethanol, 2,2'-(octylimino)bis-, Ethanol, 2,2'-(octylimino)di-, 2,2'-(Octylimino)bis[ethanol], 2,2'-(Octylimino)diethanol, Bis(2-hydroxyethyl)octylamine (+10 more)
PEG-2 CAPRYLYLAMINE (CAS 15520-05-5) is a cosmetic cosmetic ingredient functioning as Cleansing, Surfactant - Cleansing, Surfactant - Emulsifying, Viscosity. Reported NOAEL =350 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 15520-05-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
PEG-2 CAPRYLYLAMINE is classified GHS Danger (H302, H315, H318, H412) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Cleansing, Surfactant - Cleansing, Surfactant - Emulsifying, Viscosity Controlling
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-[2-hydroxyethyl(octyl)amino]ethanol
InChIKey
QZQNMMLYACBCMJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
**Allowed.** CIR reviewed PEG cocamine ingredients and requested additional genotoxicity and sensitization data; the broader PEG amine class is under ongoing review
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
1 study endpoint found for PEG-2 CAPRYLYLAMINE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =350 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Emulsifier
Surfactant (surface active agent)
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for PEG-2 CAPRYLYLAMINE.
Regulatory Flags
cosing-sourced
eu-permitted
surfactant
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-2 CAPRYLYLAMINE by CAS number or substance name.
Studies
1
Lowest NOAEL
350 mg/kg bw/day
Highest NOAEL
350 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Ethanol, 2,2'-(octylimino)bis-
Ethanol, 2,2'-(octylimino)di-
2,2'-(Octylimino)bis[ethanol]
2,2'-(Octylimino)diethanol
Bis(2-hydroxyethyl)octylamine
Diethanoloctylamine
Fomaito 2E8
Hetoxamine OT 2
N-Octyldiethanolamine
Octyldiethanolamine
2,2'-(Octylimino)bisethanol
ETHANOL,2,2'-(OCTYLIMINO)BIS
OCTANE-1,8-DIAMINE, N,N'-(2-HYDROXYETHYL)-
EINECS No.: 239-555-0
EINECS 239-555-0
Chemical Function
Surfactant (surface active agent)
Emulsifier
Viscosity modifier
Cleaning agent
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Frequently Asked Questions
Is PEG-2 CAPRYLYLAMINE allowed in the EU?
PEG-2 CAPRYLYLAMINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-2 CAPRYLYLAMINE do in cosmetics?
PEG-2 CAPRYLYLAMINE functions as: Cleansing, Surfactant - Cleansing, Surfactant - Emulsifying, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 15520-05-5.
What is the NOAEL for PEG-2 CAPRYLYLAMINE?
The NOAEL (No Observed Adverse Effect Level) for PEG-2 CAPRYLYLAMINE is =350 mg/kg bw/day based on a subchronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is PEG-2 CAPRYLYLAMINE used outside cosmetics?
PEG-2 CAPRYLYLAMINE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does PEG-2 CAPRYLYLAMINE have different safety status in cosmetics vs industrial chemicals?
PEG-2 CAPRYLYLAMINE is classified GHS Danger (H302, H315, H318, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check PEG-2 CAPRYLYLAMINE compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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